Lung acinus slideshare

Acinus or Lobule Each acinus (unit) is approximately 3.5 mm in diameter Each contains about 2000 aveloli Approximately 130,000 primary lobules in the lung 14. Alveolar Sac 15. Alveolar epithelium Two principle cell types: Type I cell, squamous pneumocyte Type II cell, granular pneumocyte 16 Upcoming SlideShare. Loading in MICROSCOPY Histological landmarks of lung acinus: • Bronchovascular bundle terminal bronchiole and arteriole - In the center of acinus • Connective tissue septa secondary lobule of Millar - At the periphery of acinus - Often ambiguous in less inflamed lung • Helpful to determine emphysema. PULMONARY ACINUS Portion of lung parenchyma supplied by a single respiratory Bronchiole. Size is 7 to 8 mm in adults 3 to 24 acini = Sec Pul. LobulePrimary Lobule: Lungparenchyma associated with asingle Alveolar duct. 4-5 Primary Lobules Acinus 4 LUNG ANATOMY 1. BY DR K.O.YASHWANT LUNG ANATOMY 2. INTRODUCTION 1)Lungs are a pair of respiratory organs situated in the thoracic cavity. 2)Each lung innervates the corresponding pleural cavity 3)In the young ,lungs are brown or grey in color 3. Definition of Obstructive Lung Disease A lung disease characterized by chronic obstruction of lung airflow that interferes with normal breathing and is not fully reversible 3. 4. -Air flow obstruction (emphysema, bronchiectasis) -Thickening of walls -Deposition at the lumen (chronic bronchitis) -Fibrosis 4. 5. 5

Intro to Respiratory Pathology (Bellot) at Ross University

Basic Pulmonary anatomy - SlideShar

  1. Developmental disorders of lungs 1. Developmental disorders of lungs Dr. Firoz A Hakkim Chest Medicine 2. Introduction Mostly congenital Consequence of disordered organogenesis May be diagnosed before birth or early in postnatal life, so corrective surgery may be applie
  2. al bronchiole and is supplied by the respiratory bronchiole and usually measure about 6-10mms in diameter. ( Osborne) The ter
  3. ACINUS Alveolar sacs Alveoli. The ultimate pulmonary unit from respiratory brochiole to alveoli is called Acinus. There are about 28 orders of division of expiration, thus reduces the work of lung inflation. 2. Waterproofing. Surfactant synthesis starts after 26 weeks o
  4. al bronchioles, anatomical and functional end of the mammalian lung respiratory tree where gas exchange occurs. Starts approximately 3 to 4 generations proximal of the bronchio-alveolar duct junction and ends about 4 generations of alveolar ducts.
  5. al bronchiole and the lung parenchyma that arises from it
  6. Lung diseases are some of the most common medical conditions in the world. Tens of millions of people have lung disease in the U.S. alone. Smoking, infections, and genes cause most lung diseases
  7. Lymphatic Drainage. Two sets of lymphatic vessels drain the lung of lymph. A subpleural lymphatic network collects the lymph from the peripheral lung tissue and drains it along the veins leading toward the hilum. There is a deeper lymphatic system that originates around the bronchi and the bronchioles. The deep system joins the lymphatics.
FlashPath - Lung - Anatomy

Adenocarcinoma of the lung is a type of non-small cell lung cancer. It occurs when abnormal lung cells multiply out of control and form a tumor. Eventually, tumor cells can spread (metastasize) to other parts of the body including the. lymph nodes around and between the lungs. liver CHRONIC OBSTRUCTIVE PULMONARY DISEASE 1. TINA THANKACHAN 2. COPD is also known as chronic obstructive lung disease (COLD), chronic obstructive airway disease (COAD), chronic airflow limitation (CAL) and chronic obstructive respiratory disease (CORD) Chronic obstructive pulmonary disease (COPD) refers to chronic bronchitis and emphysema, a pair of two commonly co-existing diseases of the lungs.

The H&E stain demonstrates a micropapillary pattern, which is a poor prognostic factor. Lung adenocarcinoma is associated with exposure to radon, not benzene, and is typically found in the peripheral regions or upper lobes of the lung. This cancer is also more common in women than in men and most frequently metastasizes to the brain, not the liver The human lung consists of 5 lobules and 10 bronchopulmonary segments. Arranged adjacent to each segment are lung lobules composed of 3-5 terminal bronchioles. Each bronchiole supplies the smallest structural unit of the lung, the acinus, which consists of alveolar ducts, alveolar sacs, and alveoli The lung root is a collection of structures that suspends the lung from the mediastinum. Each root contains a bronchus, pulmonary artery, two pulmonary veins, bronchial vessels, pulmonary plexus of nerves and lymphatic vessels. All these structures enter or leave the lung via the hilum - a wedge shaped area on its mediastinal surface The right lung is shorter and wider than the left lung, and the left lung occupies a smaller volume than the right. The cardiac notch is an indentation on the surface of the left lung, and it allows space for the heart (Figure 1). The apex of the lung is the superior region, whereas the base is the opposite region near the diaphragm To license this video for patient education or content marketing, visit: https://healthcare.nucleusmedicalmedia.com/contact-nucleusRef: ANS00400#LungAnatomy.

FlashPath - Lung - Emphysema - SlideShar

Hemosiderosis is characterized by small, ill-defined nodules or by coarse reticular areas of increased opacity with a bias for the middle and lower lung regions. Ossification manifests as densely calcified, 1-5-mm nodules, mainly in the middle and lower lungs, with a tendency for confluence and the occasional presence of trabeculae pulmonary acinus is the region of lung supplied by a single terminal bronchiole secondary lobule = five to ten acini, considered to be the smallest radiographically identifiable unit of lung Anatomic Classification of Emphysema : classified anatomically into 4 subtypes, which are distinct entities What are interstitial opacities? Interstitial - involvement of the supporting tissue of the lung parenchyma resulting in fine or coarse reticular opacities or small nodules. Atelectasis - collapse of a part of the lung due to a decrease in the amount of air in the alveoli resulting in volume loss and increased density. Click to see full answer Immunohistochemistry is a widely available technique that is less challenging and can provide clinically meaningful results quickly and cost-efficiently in comparison with other techniques. In addition, immunohistochemistry allows for the evaluation of cellular localization of proteins in the contex TB. TB of the lung is an infection caused by mycobacterium TB with two phases - an activation phase and a reactivation phase adenopathy a. key Dx feature upper or Rt middle lobe involvement initial exudative phase, vol loss instead of exp hypersensitivity rxn causes chronic inflam phase caseation necrosis after 6 wks

Technical aspect of hrct; normal lung anatomy - SlideShar

Most lung cancers are non-small cell lung cancers, and most non-small lung cancers are adenocarcinomas. This form of lung cancer accounts for more than 30 percent of all lung cancers and about half of all non-small cell lung cancers.. Adenocarcinoma forms in glands that secrete mucus.Other than the lungs, adenocarcinoma is most prevalent in cancers found in the prostate, pancreas, esophagus. Acinar dysplasia: the lung lobules are composed of irregular air spaces lined throughout by ciliated columnar epithelium and separated by abundant loose stroma. In reported cases, the lungs have shown varying degrees of hypoplasia, ranging from 40% to 100% of the predicted lung weight. 34 , 35 , 36 The lobules are separated by prominent septa. Chronic obstructive pulmonary disease (COPD) is characterised by poorly reversible airflow obstruction and an abnormal inflammatory response in the lungs. The latter represents the innate and adaptive immune responses to long term exposure to noxious particles and gases, particularly cigarette smoke. Most patients with ARDS recover lung function within 3-4 weeks, very few progresses into fibrotic phase that may require long-term support on mechanical ventilators and/or supplemental oxygen. There is extensive alveolar-duct and interstitial fibrosis. Marked disruption of acinar architecture leads to emphysema-like changes, with large bullae

Video: LUNG ANATOMY - SlideShar

Development of lung 1. DEVELOPMENT OF LUNG By Dr.S.Sesha Sai PG - Pulmonary Medicine 2. Lung development has traditionally been divided into five stages based on histologic appearance. 1. Embryonic 3-7 wks 2. Pseudoglandular 5-17 weeks 3. Canalicular 16-26 weeks 4. Saccular 24-38 weeks 5 SlideShare Explorar Pesquisar Voc CONSOLIDATION • Replacement of air in one or more acini by fluid or solid material • Smallest unit of consolidated lung is acinus casts 7mm diameter shadow • Confluence occurs 38 Slide 9 of 59 of COPD (Chronic obstructive Pulmonary Disease) PowerPoint Presentation -asla

Obstructive Lung Diseases - SlideShar

Developmental disorders of lungs - SlideShar

The pulmonary acinus is represented by the structures arising from a single terminal bronchiole and consists of respiratory bronchioles and alveoli. Respiratory bronchioles are lined by simple cuboidal epithelium and participate in gas exchange. They lead into alveolar ducts. Alveolar sacs arise as saccular outpouchings from the alveolar ducts and respiratory bronchioles In general, each lung has 10 segments: the upper lobes contain 3 segments, the middle lobe / lingula 2 and the lower lobes 5. Bilaterally, the upper lobes have apical, posterior and anterior segments and the lower lobes superior (apical) and 4 basal segments (anterior, medial, posterior and lateral). With this basic symmetric anatomy shared. DR RIKIN HASNANI Pulmonary complication in Pancreatiti

The lungs contain 200-300 million alveoli that are reached via 23 generations of airways. The volume in the lungs after an ordinary expiration is called functional residual capacity (FRC) and is approximately 3-4 L. The lung is elastic and force (pressure) is needed to expand it and to overcome the resistance to gas flow in the airways. This pressure can be measured as pleural minus. The lungs are the foundational organs of the respiratory system, whose most basic function is to facilitate gas exchange from the environment into the bloodstream. Oxygen gets transported through the alveoli into the capillary network, where it can enter the arterial system, ultimately to perfuse tissue. The respiratory system is composed primarily of the nose, oropharynx, larynx, trachea. 8253/2 -Lung Only -Adenocarcinoma in situ, mucinous 8257/3 -Lung Only -Minimally Invasive Adenocarcinoma 8845/2 -Lung Only -Pulmonary Myxoid Sarcoma with EWESRq-CREB1 translocation 8551/3 -Lung Only -Acinar Adenocarcinoma 8253/3 -Lung Only -Invasive Mucinous Adenocarcinom

Technical aspect of hrct; normal lung anatomy & hrct

Acinus Lung

Acinar dysplasia is the most severe of these conditions, because the lung is most underdeveloped at the time of birth, containing only airway structures and no alveoli. Patients with acinar dysplasia are typically born at full term with small lungs and severe respiratory failure. Radiographs typically show low lung volumes with diffuse opacity Physical Exam • Percuss: - Diaphragmatic excursion • Percuss the level of the diaphragm on full expiration and on full inspiration, noting the difference in distance in centimeters between the two. 1) have person exhale fully and then hold breath as you percuss from resonance (over lung tissue) to dullness (over diaphragm). Mark this area. 2) Now, have the person inhale and hold breath. Pulmonary edema is frequently classified as hydrostatic edema (e.g., cardiogenic pulmonary edema) or edema caused by increased capillary permeability (e.g., noncardiogenic pulmonary edema or capillary leak). Often, chest radiographs of patients with pulmonary edema are not as easily classified in such a dichotomous fashion Footnote 35 in the latest edition of the Terminologia Histologica (FICAT, ) indicates that 'in some parts of the world the term acinus and alveolus are used synonymously while in others, the terms are used differently'.This inconsistent terminology in this field of human microscopic anatomy has been found in a variety of old and recent textbooks, reference books, medical dictionaries, some.

Shwachman syndrome is a rare genetic disorder with multiple and varied manifestations. The disorder is typically characterized by signs of insufficient absorption (malabsorption) of fats and other nutrients due to abnormal development of the pancreas (pancreatic insufficiency) and improper functioning of the bone marrow (bone marrow dysfunction. The relationship between nasal cavity and lung aeration is ipsilateral during the pulmonary cycle. (b) The turbinates contain thick-walled nasal erectile tissue and are is usually covered by respiratory mucosa Type 0 is acinar dysplasia or agenesis and is incompatible with survival. Type I is the large-cyst type on imaging and typically affects a single lobe with cyst size 1-10 cm ( Figure 17 ). Type II is the small cyst type on imaging, which has small lesions < 2.0 cm. Type III is a solid-appearing lesion with microcysts that coalesce.

Acinar tissue with an intralobular ductule in cross section, human pancreas (H & E). Note the single layer of cuboidal duct cells and the nearly complete absence of collagen in the wall of this ductule. Compare this with Figures 19 and 27, where intralobular ductules are shown in longitudinal section. The lumen of the ductule contains a pink. The pulmonary acini are supplied by the respiratory bronchioles and comprise the largest lung unit that participates in gas exchange. The lobular bronchiole (which is a preterminal or terminal bronchiole), the accompanying pulmonary arteriole, and the central lymphatics that run in the peribronchovascular interstitium form the. The Lung Flute is a small, self-powered audio device approved by the United States Food and Drug Administration in 2006 as adjunct therapy for sputum induction procedures

Bronchi are plural for bronchus and represent the passageways leading into the lungs.The first bronchi branch from trachea, and they are the right and left main bronchi.These bronchi are the widest and they enter the lung. After entering the lungs, the bronchi continue to branch further into the secondary bronchi, known as lobar bronchi, which then branch into tertiary (segmental) bronchi Emphysema is a lung condition that causes shortness of breath. In people with emphysema, the air sacs in the lungs (alveoli) are damaged. Over time, the inner walls of the air sacs weaken and rupture — creating larger air spaces instead of many small ones. This reduces the surface area of the lungs and, in turn, the amount of oxygen that. spiratory support, which expands the lung volumes, and low lung volumes are not a reli - able feature of SDD in modern practice [14, 18]. Exogenous surfactant is often admin-istered via endotracheal tube to treat SDD, which may result in normalization of lung volumes (Fig. 2). Occasionally, acini receiv-ing exogenous surfactant can become over Features of left lower lobe consolidation on CXR include: opacification of the mid and/or lower zones, and occasionally even upper zone. normal (clear and distinct) left superior mediastinal contour ( silhouette sign ), especially the aortic arch. obscuration of the left hilum, particularly the inferior hilum in apical segment consolidation

Lecture - Respiratory Development - Embryolog

Prostate cancer is the second leading cause of cancer death in men, behind only lung cancer. 1 More than 95% of all diagnosed malignant prostate cases are represented by acinar adenocarcinoma.2, 3 In some cases, the proper diagnosis of prostatic neoplasia can be challenging, and the differential diagnosis should include atypical nonmalignant lesions. 4 Atrophy (especially partial) is the most. Diffuse thick rind-like or nodular pleural thickening which may extend into the lung (Indian J Radiol Imaging 2013;23:313) May be associated with unilateral pleural effusion and ipsilateral lung volume loss Adenocarcinoma of lung / metastatic carcinoma Lung primary: main finding is a lung mass / nodule which may extend to the pleur

Serous acinus definition of serous acinus by Medical

Atypical cells can change back to normal cells if the underlying cause is removed or resolved. This can happen spontaneously. Or it can be the result of a specific treatment. Atypical cells don't necessarily mean you have cancer. However, it's still important to make sure there's no cancer present or that a cancer isn't just starting to develop Emphysema is a progressive disease, which means it continues to get worse. As the condition progresses, the lungs lose their ability to absorb oxygen and release carbon dioxide. Breathing becomes more difficult. A person feels easily short of breath, like he or she is not getting enough air Voce in Pubblico. Come parlare in pubblico: come superare la paura e aumentare la sicurezz

Definition / general. Complication of mechanical ventilation and oxygen therapy for treatment of neonatal respiratory distress syndrome. Infants almost always < 1200 gram birth weight and < 30 weeks gestation. Definition: requirement for supplemental oxygen for longer than 28 days of age, and a postmenstrual age of at least 36 weeks ( eMedicine Lung cancer or bronchogenic carcinoma refers to tumors originating in the lung parenchyma or within bronchi. It is one of the leading causes of cancer-related deaths in the United States. Since 1987, lung cancer is responsible for more deaths in women than breast cancer. It is estimated that there are 225,000 new cases of lung cancer in the United States annually and approximately 160,000 die. Round atelectasis , also known as rounded atelectasis , folded lung or Blesovsky syndrome , is an unusual type of lung atelectasis where there is infolding of a redundant pleura. The way the lung collapses can at times give a false mass-like appearance. On this page: Article: Epidemiology. Pathology. Radiographic features. History and etymology M. tuberculosis is an aerobic, nonmotile, non-spore-forming rod that is highly resistant to drying, acid, and alcohol. It is transmitted from person to person via droplet nuclei containing the organism and is spread mainly by coughing. A person with active but untreated TB infects approximately 10-15 other people per year

EmphysemaFlashPath - Lung - Histology

Non-cardiogenic pulmonary edema is a classification of pulmonary edema where the underlying etiology is not due to left ventricular dysfunction. Causes include: fluid overload. pulmonary edema with acute asthma. post-obstructive pulmonary edema /postintubation pulmonary edema/ negative pressure pulmonary edema Idiopathic pulmonary fibrosis (IPF) is a clinical syndrome and considered the most common and the most lethal form of pulmonary fibrosis corresponding to the histologic and imaging pattern of usual interstitial pneumonia. It is more common in elderly men and diagnosed by: histological or imaging pattern of usual interstitial pneumonia (UIP) and. CASE NUMBER 39 [DigitalScope] Clinical History: A 58-year-old female had been hemiplegic on the right for a period of 3 months prior to death. She developed fever and dyspnea several days prior to death. Gross: There was a thrombosis of the left internal carotid artery with infarction of the left cerebral hemisphere. There was a massive embolus of the right pulmonary artery

Prostate cancer is the second leading cause of cancer death in men, behind only lung cancer. In some cases, the proper diagnosis of prostatic neoplasia can be challenging, and the differential diagnosis includes atypical nonmalignant lesions such as atrophy, atypical adenomatous hyperplasia (AAH), and atypical small acinar proliferation (ASAP) In this case, the fat extends into acinus zone 2 or the midzone of the hepatic lobule (H&E, ×4). Alcoholic foamy degeneration is an uncommon form of ALD steatosis. The pathological appearance comprises microvesicular steatosis in virtually all hepatocytes, similar to that seen in diseases with mitochondrial dysfunction, such as Reye syndrome. Hepatocellular Carcinoma (Liver Cancer): Anatomy Anatomy The liver is the largest organ in the abdominal cavity and the most complex. It consists of a myriad of individual microscopic functional units call lobules Lung pathology Dr. Emile Musoni SoM-CMHS No SlideShare. 0 A partir de incorporações. 0 Emphysema Emphysema is classified according to its anatomic distribution within the lobule; as described earlier, the acinus is the structure distal to terminal bronchioles, and a cluster of three to five acini is called a lobule .. Slide 9-3 Lung, centrilobular emphysema; Slide 9-4 Colon, diverticulosis . Slide Descriptions. Slide 1-01. Necrosis, pancreas and fat [DigitalScope] The underlying cause of necrosis in this tissue is the thrombosis present in the vessel at the lower left of the slide. This has led to coagulative necrosis within pancreatic tissue. Few acini are

The acinus is comprised of respiratory airways and forms functional tissues (gas exchange units) of lung. The alveolar ducts are small tubes supported by a rich matrix of elastic and collagen fibres. The distal ends of alveolar ducts open into the alveolar sac which is made up by alveoli Emphysema: dilation/destruction of airway distal to terminal bronchiole (acinus) CD8+ T-lymphocytes, neutrophils, and CD68+ monocytes/macrophages. Chronic bronchitis: Excess mucous, airway thickening. CD8+ T-lymphocytes, neutrophils, and CD68+ monocytes/macrophage Approach to interstitial lung disease: Dr Bhavin Jankharia's talk. On December 2, 2017. January 21, 2018. By caferoentgen In In a nutshell: Lecture notes. Here are the notes based on the talk by Dr Jankharia. There are a couple of links as well at the end to read more from, and links to two ppts put up on this topic on slideshare by Dr.

COPD ppt - Free download as Powerpoint Presentation (.ppt / .pptx), PDF File (.pdf), Text File (.txt) or view presentation slides online. Chronic Obstructive Pulmonary Disease is a lung disease characterized by chronic obstruction of lung airflow that interferes with normal and is not fully reversible Bronchogenic carcinoma is any type or subtype of lung cancer. It's a fairly common cancer. Learn the symptoms and what treatment options are available

The main consequence of peripheral lung injury is the development of heterogeneities that affect the efficacy of respiratory gas exchange and ventilatory distribution. 34,35. Patients with ARDS have lung regions with low V̇/Q̇ (and high P ACO 2) that usually coexist with others having high V̇/Q̇ (and low P ACO 2). The combination of these 2. Bronchiectasis (plural: bronchiectases) is defined as an irreversible abnormal dilatation of the bronchial tree. It has a variety of underlying causes, with a common etiology of chronic inflammation. High-resolution CT is the most accurate modality for diagnosis. On this page: Article: Epidemiology. Clinical presentation Lung Development - Embryology Made Easy. Remember the mnemonic - Every Premature Child Takes Air . The development of lungs comprises of 5 distinct stages: The first and last stages, i.e. Embryonic and Alveolar stages are almost 5 weeks in duration (but alveolar stage continues after birth to childhood) and the middle 3 stages, i.e. 11/15/2011 4 Lung Cancer Facts Lung cancer accounts for more deaths than any other cancer in both men and women. Since 1987, more women have died each year from lung cancer than from breast cancer. Lung cancer causes more deaths than the next three common cancers combined (colon, breast, prostate). Smoking contributes to 80% and 90% of lung cancer deaths i

PPT - Respiratory System PowerPoint Presentation, free

Pneumonia is an important cause of morbidity and mortality in adults and children. The most useful classification is based on the site of acquisition: community-acquired (CAP) or hospital-acquired pneumonia (HAP). CAP is caused by a small range of key pathogens and the most important issue in the management of the disease is the care setting. Chapter 6 Management of respiratory diseases Stephanie Enright and Fiona M. Schreuder Note Other relevant information such as the active cycle of breathing technique (ACBT) and basic respiratory anatomy and physiology of the lungs can be found in Chapter 9. Introduction Diseases of the respiratory system are a major cause of illness worldwide and ar Stage 1 lung cancer falls under the localized classification. According to SEER data from 2010 to 2016, stage 1 NSCLC has a five-year survival rate of 59%. 4 . The downside to the SEER classification system is that allows for a significant overlap in definitions